Thursday, June 26, 2025

Time Event
08:30 - 09:30 arrival and registration (CBI entrance)  
09:30 - 09:40 welcome address (amphitheatre CBI 0028) - the organizers  
09:40 - 10:40 Microtubules and cell division (amphitheatre CBI 0028)  
09:40 - 09:55 › CELL DIVISION GEOMETRY IN TISSUE MORPHOGENESIS - Laura Ruiz, Institut de Biologie du Développement de Marseille  
09:55 - 10:10 › Insights into new forces involved in spindle positioning in Drosophila neural stem cells - Imane NAOUADIR, Institut de Génétique et Développement de Rennes  
10:10 - 10:25 › Role of microtubule-associated BORG2/CDC42EP3 in CDC42-dependent control of mitosis - Béatrice BENOIT, Université Paris-Saclay, UFR Pharmacie, Moissan, Orsay  
10:25 - 10:40 › Microtubule stiffening by doublecortin-domain protein ZYG-8 contributes to spindle orientation during C. elegans zygote division. - Hélène Bouvrais, Institut de Génétique et Développement de Rennes  
10:40 - 11:15 Coffee break (CBI entrance)  
11:15 - 12:00 Microtubule isotypes and posttranslational modifications (amphitheatre CBI 0028)  
11:15 - 11:30 › MAPping the β-Tubulin Tyrosination Landscape in Trypanosoma brucei via TurboID - JEREMY VINCENT, University of Montpellier, CNRS, IRD, MiVEGEC  
11:30 - 11:45 › Reduced tubulin polyglutamylation affects neuronal function and causes late-onset neurodegeneration - Shreyangi Chakraborty, Institut Curie, PSL Research University, CNRS UMR3348, Orsay, France, Université Paris-Saclay, CNRS UMR3348, Orsay, France  
11:45 - 12:00 › Tubulin isotypes polymerise into sectioned microtubules that locally regulate protein binding - Marcus Braun, Institute of Biotechnology, Czech Academy of Sciences, BIOCEV, 25250 Vestec, Prague West  
12:00 - 13:00 Lunch  
13:00 - 14:15 poster session (CBI entrance)  
13:00 - 14:15 › Microtubule reorganization in epidermal keratinocytes - Keying GUO, Centre for Integrative Biology - CBI - Andreas MERDES, Centre for Integrative Biology - CBI  
13:00 - 14:15 › Interplay between tubulin (de)tyrosination and autophagy in neurons and the brain. - Samar ISMAIL, Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France  
13:00 - 14:15 › Spatial and temporal control of microtubule polyglutamylation in neurons - Eva Desvigne-Hansch, Intégrité du génome, ARN et cancer  
13:00 - 14:15 › Elucidating β2-tubulin detyrosination and the tyrosination-dependent MAP code in Leishmania parasites - Rosa Milagros Corrales, University of Montpellier, CNRS, IRD, MiVEGEC  
13:00 - 14:15 › The role of Microtubule-Associated Proteins in organising microtubule bundles in cells using expansion microscopy  
13:00 - 14:15 › Posttranslational encoding of microtubules provides unique recognition patterns for associated proteins - Arya Krishnan, Institut Curie, Université PSL, CNRS UMR3348, F-91401 Orsay, Université. Paris-Saclay, CNRS UMR3348, F-91401 Orsay  
13:00 - 14:15 › The kinesin Kip2 promotes microtubule growth using a bipartite polymerase module to deliver tubulin to microtubule plus-ends - Didier Portran, Centre de recherche en Biologie cellulaire de Montpellier  
13:00 - 14:15 › Quality control of spindle-associated proteins - Simos Nadalis, Centre de Recherche en Biologie cellulaire de Montpellier  
13:00 - 14:15 › Determining the mechanistic roles of tubulin polyglutamylation in Purkinje-cell degeneration  
13:00 - 14:15 › Determining the mechanistic roles of tubulin glutamylation in the regulation of neuronal functions - Danilo Lopes, Institut Curie, Université Paris-Saclay  
13:00 - 14:15 › VASH2-SVBP detyrosinating enzyme modulates microtubule dynamics  
13:00 - 14:15 › Role of tubulin (de)tyrosination in the Microtubule-Actin crosstalk in the dendritic spines - Aditi Sharma, Grenoble Institut des Neurosciences  
13:00 - 14:15 › MBAPs link brassinosteroid signaling and cortical microtubules - Satoshi FUJITA, LRSV-Signalisation Cellulaire et Ubiquitination  
13:00 - 14:15 › Remodelage des microtubules et du centrosome en quiescence - Aurélie Massoni-Laporte, Institut de biochimie et génétique cellulaires  
14:15 - 15:30 Microtubules in differentiation and development (amphitheatre CBI 0028)  
14:15 - 14:30 › Asymmetric microtubule nucleation from Golgi stacks promotes opposite microtubule polarity in axons and dendrites - AKILA YAGOUBAT MERAH, Université Sorbonne Paris Cité  
14:30 - 14:45 › Cytoskeletal dynamics at synapses: characterization of novel microtubular regulators and their potential role in resilience to neurodegeneration - Martina Aleman, Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000 Grenoble, France  
14:45 - 15:00 › Regulation of focal adhesion turnover by the +TIP NAV1 during cell migration and axonal growth cone motility - Jérôme Boudeau, Centre de recherche en Biologie cellulaire de Montpellier  
15:00 - 15:15 › Centrosomal vs Golgi microtubules : Key players in osteoclast formation and function ? - Camille GORLT, Unité de biologie Moléculaire, Cellulaire et du Développement, Institut de pharmacologie et de biologie structurale  
15:15 - 15:30 › Centrosome and Microtubule Function in Dendritic Cells Orchestrate Adaptive Immune Activation - Eva Kiermaier, University of Bonn  
15:30 - 16:00 Coffee break (CBI entrance)  
16:00 - 17:00 Microtubules and diseases (amphitheatre CBI 0028)  
16:00 - 16:15 › A hypothetical functional amyloid of the tau protein - Benoit Gigant, Institut de Biologie Intégrative de la Cellule  
16:15 - 16:30 › Towards a new anti-cancer therapy targeting microtubules - Audrey Roussel, Centre de biophysique moléculaire  
16:30 - 16:45 › Tau condensation on microtubules generates specific microenvironment - Eva Lanska, Institute of Biotechnology of the Czech Academy of Sciences - Aniruddha Nagarajan, The Institute of Mathematical Sciences, Chennai, Tamil Nadu, India - Tereza Humhalova, Faculty of Science, Charles University, Prague, Czechia - Valerie Siahaan, Institute of Biotechnology of the Czech Academy of Sciences - Jochen Krattenmacher, Institute of Biotechnology of the Czech Academy of Sciences - Lenka Libusova, Faculty of Science, Charles University, Prague, Czechia - Carsten Janke, Institut Curie, PSL Research University,, Université Paris-Saclay - Zdenek Lansky, Institute of Biotechnology of the Czech Academy of Sciences - Marcus Braun, Institute of Biotechnology of the Czech Academy of Sciences - Sandeep Choubey, The Institute of Mathematical Sciences, Chennai, Tamil Nadu, India  
16:45 - 17:00 › PYRUVATE-MEDIATED MODULATION OF PRIMARY CILIA BIOLOGY IN COLONIC FIBROBLASTS - Maya Sarieddine, Institut de Génétique Moléculaire de Montpellier  
17:00 - 17:15 Break (CBI entrance)  
17:15 - 18:15 keynote lecture (amphitheatre CBI 0028)  
18:15 - 19:30 drinks and posters (max. width 90cm x height 135cm) (CBI entrance and IBCG seminar rooms)  
19:30 - 21:00 Dinner  

Friday, June 27, 2025

Time Event
09:15 - 10:30 Microtubule assembly (amphitheatre CBI 0028)  
09:15 - 09:30 › Beyond mitosis: targeted degradation uncovers novel interphase functions of augmin. - Marcos Fariña-Mosquera, Institute for Research in Biomedicine [Barcelona, Spain]  
09:30 - 09:45 › C- and D-type lateral interactions weaken the microtubule lattice - Matthieu Benoit, Institut de Génétique et Développement de Rennes (IGDR) UMR 6290, MiToS team  
09:45 - 10:00 › Mechanistic Dissection of γTuRC Activation by Centrosomin Motif 1 (CM1) - Cláudia Fernandes Brito, Centro de Regulación Genómica  
10:00 - 10:15 › Xenopus spermatid microtubules contain an internal helix - Céline Callens, Institut de Génétique et Développement de Rennes  
10:15 - 10:30 › Stable GDP-tubulin islands rescue dynamic microtubules - Virginie Stoppin-Mellet, Grenoble Institut des Neurosciences  
10:30 - 11:00 Coffee break (CBI entrance)  
11:00 - 12:00 Microtubule-dependent motors and transport (amphitheatre CBI 0028)  
11:00 - 11:15 › Precise control of microtubule structure and intracellular trafficking in living cells and behaving animals - Yu-Chun Lin, National Tsing Hua University [Hsinchu]  
11:15 - 11:30 › Spatial activation of Kinesin-1 by Ensconsin shapes microtubule networks via ncMTOCs recruitment - Laetitia Bataillé, Institut de Génétique et Développement de Rennes (IGDR), Univ Rennes, CNRS, UMR 6290, INSERM ERL U1305  
11:30 - 11:45 › NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends - Sabina Colombo, Centro de Regulación Genómica (CRG)  
11:45 - 12:00 › Kinesin-12 KLP-18 contributes to the kinetochore-microtubule poleward flux during the metaphase of C. elegans one-cell embryo. - Mathis Da Silva, Institut de Génétique et Développement de Rennes  
12:00 - 14:00 Lunch  
14:00 - 14:45 Microtubule inhibitors (amphitheatre CBI 0028)  
14:00 - 14:15 › A new nanoDSF approach to anti-tubulin compounds screening - Philipp TSVETKOV, Institut de neurophysiopathologie  
14:15 - 14:30 › Effects of oxfendazole, a microtubule-targeting agent, on the development of filarial parasites - Linda KOHL, UMR7245 MCAM, MNHN-CNRS  
14:30 - 14:45 › Peptide-based covalent inhibitor of tubulin detyrosination promotes mesenchymal-to-epithelial transition in lung cancer cells - Ghislain Gillard, Institut de Génétique Humaine  
14:45 - 15:30 prizes for junior presenters, planning of future meetings, closing remarks (amphitheatre CBI 0028)  
CNRS CCSD Sciencesconf